Immunity &
Autoimmunity Testing
Identify the hidden immune triggers behind chronic inflammation, allergy, and autoimmunity.
Your immune system is your body’s first line of defence, protecting against infection, inflammation, and environmental triggers. When it becomes overactive or misdirected, it can contribute to chronic inflammation, autoimmune disorders, or heightened allergy responses. Persistent immune activation may be driven by environmental exposures, infections, intestinal permeability, or molecular mimicry, where the immune system mistakenly targets the body’s own tissues.
Functional laboratory testing can help differentiate whether immune activity stems primarily from allergy, autoimmunity, or infection, allowing for a clearer understanding of immune balance and inflammatory drivers.
Not sure if immune testing is right for you?
Book a free 10-minute discovery call to discuss how we might work together, or dive in fully with an Initial consultation.
Standout immune & autoimmune testing
Autoimmune Profile (Comprehensive)
A broad antibody screen assessing multiple markers of autoimmune reactivity, to provide insight into patterns of immune activation that may contribute to autoimmune-type or chronic inflammatory presentations.
Comprehensive assessment helps clarify the degree and type of immune involvement, supporting early detection of immune imbalance and tailored management strategies.
IgE Mould Allergy Test
Assesses IgE (immediate-type allergy) reactions to 12 common mould species that can trigger respiratory or systemic allergy symptoms.
Helps distinguish mould allergy from mould toxicity and guides appropriate environmental and immune support.
Immunoserology of Lyme Panel A
Measures IgG and IgM antibodies to Borrelia burgdorferi and related tick-borne co-infections.
Useful for investigating persistent fatigue, joint pain, neurological or immune symptoms following tick exposure.
MycoTOX Profile
The MycoTOX Profile measures toxins produced by mould that are excreted in urine. These mould toxins can contribute to symptoms such as fatigue, headaches, poor concentration, or breathing difficulties.
When used alongside an IgE Mould Allergy Test, it helps to show whether symptoms are linked to mould sensitivity, toxin exposure, or both — offering a more complete picture of mould-related health effects.
Jump to our Toxicity Testing page to learn more →
Autoimmune Profile (Comprehensive)
The Autoimmune Profile (Comprehensive) provides an early and detailed assessment of immune reactivity that may underlie autoimmune disease.
This blood test evaluates a core group of antibodies associated with systemic and organ-specific autoimmune processes, offering insight into immune activation even before clinical symptoms become advanced.
What it Measures:
This comprehensive antibody screen includes the following analytes:
Anti-Nuclear Antibody (ANA IgG) - Detects antibodies directed against components of the cell nucleus. A key screening marker for systemic autoimmune conditions such as lupus and connective-tissue disorders.
Extractable Nuclear Antigen (ENA IgG) - Identifies specific nuclear antigens targeted in conditions like Sjögren’s syndrome, scleroderma, and mixed connective-tissue disease.
Double-Stranded DNA (dsDNA IgG) - Highly specific for systemic lupus erythematosus (SLE); helps confirm lupus activity.
Rheumatoid Factor (RF) Autoantibody often elevated in rheumatoid arthritis and other chronic inflammatory conditions.
Actin (Smooth Muscle) IgG - Indicates autoimmune activity against smooth-muscle tissue, commonly seen in autoimmune hepatitis.
Mitochondrial IgG - Suggests autoimmune attack on mitochondrial antigens, seen in conditions such as primary biliary cholangitis.
C1Q Immune Complex - Reflects circulating immune-complex formation; may be elevated in systemic lupus and other immune-complex disorders.
Who Benefits:
Individuals who experience unexplained inflammation or symptoms consistent with autoimmune activation, such as:
Persistent fatigue, joint pain, or muscle aches
Chronic inflammation without clear cause
Rashes, photosensitivity, or hair loss
Liver enzyme abnormalities or digestive discomfort
Family history of autoimmune or connective-tissue disease
Why It’s Useful:
Early identification of autoimmune reactivity allows for:
Targeted assessment of specific disease patterns
Timely referral or integrative management strategies
Monitoring of antibody trends during treatment or remission
Guidance for dietary, environmental, and immune-modulating interventions
Sample: Blood sample at Laverty pathology
Turnaround: 3-4 weeks.
Supplier: Immunosciences Lab (USA) via RN Labs, Australia.
To find out if your symptoms may be autoimmune related, and whether this test is suitable for you,
IgE Mould Allergy Test
The IgE Mould Allergy Test measures immediate-type (IgE-mediated) immune responses to common environmental moulds.
It identifies whether an allergic immune reaction is occurring in response to mould exposure, helping clarify if respiratory, skin, or systemic symptoms are driven by mould-related allergy rather than other triggers.
What it Measures:
This serum test quantifies IgE antibodies directed against 12 common indoor and outdoor mould species known to provoke allergic or inflammatory reactions.
Alternaria tenuis (alternata) - Common outdoor mould associated with asthma; thrives in damp, poorly ventilated areas.
Aspergillus fumigatus - Grows on damp building materials, compost, stored grains; associated with asthma and allergic bronchopulmonary aspergillosis.
Bipolaris spicifera - Soil- and plant-derived mould linked to allergic sinusitis, dermal and respiratory infections.
Candida albicans - Yeast normally present in the gut and skin; overgrowth may stimulate IgE reactivity and systemic symptoms.
Cladosporium herbarum - Ubiquitous indoor/outdoor mould found on walls, HVAC systems, and foodstuffs.
Epicoccum purpurascens - Common agricultural mould that can contaminate food and textiles; seasonal exposure peaks in dry autumns.
Fusarium moniliforme / F. oxysporum - Found in cereal grains and water-damaged buildings. May contribute to respiratory and hypersensitivity symptoms.
Helminthosporium halodes - Grain contaminant thriving in warm, moist environments; occasionally found in water-damaged buildings.
Mucor racemosus - Found in soil, dairy, spices, nuts, and mouldy foods; agricultural workers are often exposed.
Penicillium notatum (chrysogenum) - Common in damp buildings and food; may cause asthma or respiratory infection.
Phoma betae - Found in soil, food, and water; opportunistic pathogen and allergen in crops and stored produce.
Stemphylium botryosum - Present on grains, tomatoes, and farm crops; exposure peaks during ragweed season.
Who Benefits:
Individuals with suspected mould-related allergy or exposure, who experience:
Nasal congestion, sneezing, or watery / itchy eyes
Chronic cough, asthma, or sinus inflammation
Fatigue, headaches, or cognitive fog linked to mouldy environments
Skin irritation or eczema flares in damp settings
History of living or working in buildings with moisture damage.
Why it’s Useful:
Confirms whether mould exposure is triggering IgE-mediated allergy.
Distinguishes allergic reactivity from toxic (mycotoxin) effects.
Guides personalised interventions such as remediation strategies, targeted desensitisation, or immune support.
Sample: Blood sample at Laverty pathology
Turnaround: 3-4 weeks.
Supplier: Immunosciences Lab, USA via RN Labs, Australia
Related Testing
The IgE Allergy Mould Tests complements the MycoTOX Profile, which measures mycotoxin metabolites. Together they provide a fuller picture of mould exposure and immune impact.
For a broader assessment of internal mould and environmental toxin exposure, explore the Toxicity Testing – MycoTOX & TOXDetect Profiles here →
To find out if mould exposure is contributing to allergy or inflammation, and whether this test is suitable for you,
Immunoserology of Lyme Panel A
The Immunoserology of Lyme Panel A is a highly specific blood test that measures both IgG and IgM antibodies directed toward multiple tick-borne antigens associated with Lyme disease (Borrelia burgdorferi and related subspecies).
This advanced immunoserological panel improves the accuracy of Lyme detection by assessing antibodies produced both in culture and in vivo during infection, supporting early identification of complex or chronic tick-borne illness.
What it Measures:
A patented immunoserological assay assessing antibodies to multiple Lyme-specific, Borrelia subspecies, and co-infection antigens.
Lyme-Specific Antibodies - B. burgdorferi Antigens (IgG, IgM); OspA + OspC Peptides (IgG, IgM); OspE Peptides (IgG, IgM); Leukocyte Function-Associated Antigen (IgG, IgM); Immunodominant Protein (IgG, IgM); Variable Major Protein (IgG, IgM).
Borrelia Subspecies Antibodies - B. sensu stricto (IgG, IgM); B. garinii (IgG, IgM); B. afzelii (IgG, IgM).
Co-Infection Antibodies - Babesia (IgG, IgM); Ehrlichia (IgG, IgM); Bartonella (IgG, IgM).
Who Benefits:
This panel is suitable for individuals who:
Have a history of tick bite or reside in endemic areas
Experience chronic fatigue, joint pain, neuropathy, or migrating pain
Show overlapping symptoms with autoimmune or neurodegenerative disorders
Have unexplained inflammatory, cognitive, or immune dysregulation symptoms
Have previously received inconclusive Lyme or tick-borne results
Why it’s Useful:
Provides broad immunoserologic coverage of Borrelia species and co-infections
Detects antibodies to antigens expressed in vivo, increasing diagnostic sensitivity
Differentiates between recent, chronic, and subspecies-specific infection
Supports comprehensive case evaluation when combined with symptom assessment and other panels (e.g., Autoimmune Profile, Organic Acids Test, Hepatic Detoxification Profile)
Sample: Blood sample at Laverty pathology
Turnaround: 3-4 weeks.
If you suspect Lyme disease or chronic tick-borne infection, early identification of immune reactivity can help guide appropriate treatment and recovery strategies.
To discuss whether this test is suitable for you, book an Initial consultation →
Companion Testing
Immune dysregulation is often multifactorial. Additional testing can help clarify contributing factors:
Gut Health & Microbiome Tests – Can assess intestinal permeability, dysbiosis, and immune triggers that may be driving your inflammation. Immune regulation begins in the gut!
OMX - Organic Metabolomics Test – Can be beneficial in suspected autoimmune disorders by identifying underlying imbalances that can contribute to chronic inflammation and immune dysfunction. It helps pinpoint specific nutritional deficiencies, metabolic disruptions, and altered biochemical pathways that may be linked to an autoimmune condition. Understand how environmental and chemical exposures may be affecting your immune dysregulation.
Toxicity Panels - MycoTOX & TOXDetect - Provide a broader assessment of internal mould and environmental toxin exposure. Understand how environmental and chemical exposures may be affecting your immune dysregulation.
To discuss which combination of immune, gut, and toxicity testing is most appropriate for you, and begin a personalised plan to support long-term resilience, book an Initial Consultation →
Immunity & Autoimmune Testing FAQs
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Allergies are IgE-mediated immune reactions to external triggers (e.g., foods, moulds, pollens).
Autoimmunity occurs when the immune system mistakenly attacks the body’s own tissues, leading to chronic inflammation.
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Yes. Chronic inflammation, microbiome imbalance, or environmental exposures can activate both allergy-type and autoimmune responses simultaneously.
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Testing provides insight into specific antibody patterns, infection triggers, and immune modulation needs, enabling more targeted support beyond symptom management.
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Mould can provoke both allergic (IgE) and toxic (mycotoxin-related) immune responses. Identifying the type of reaction is key to effective treatment.
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Certain medications (antihistamines, immunosuppressants), supplements and medications may alter results. Your practitioner will guide you on any temporary discontinuations prior to collection.
Never discontinue medication without speaking with your medical practitioner.
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Your sample should be collected mid-stream from your first morning urine void before eating or drinking
You must have been asleep for at least 6 hours before completing the sample OR if this cannot be achieved, 4 hours is the minimum
You may wake up during the night but should not get out of bed. You may toss and turn but when you get out of bed, that is when the sample must be taken
Freeze sample immediately after collection
Your sample must be frozen for at least 4 hours before sending. It may be stored in the freezer for up to a week to be posted on the following Monday
Complete the sample over the weekend so it can be posted on a Monday
If you take any medications, discuss this with your practitioner prior to testing
Non-essential medicines and supplements (e.g. magnesium, fish oil, etc) should be ceased 2 days prior to sample collection, as they can affect your results. You may need to discuss this with your practitioner.
If you have collected and need to recollect, you can empty the sample, rinse with warm water and air dry, ready to complete again the following morning
If menstruating, avoid contamination of sample as this can interfere with test results. You may need to wait before collecting. Samples that are visibly contaminated with blood (red, pink, or brown in colour) will be rejected and a new sample requested.
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Functional pathology tests are an extremely comprehensive assessment of what is potentially occurring within a person’s body. They often test very different things than what general pathology tests do. From the results, your practitioner may be able to develop more specific treatment plans that address the cause of your symptoms.
Ready to better manage your immune responses?
Understanding what drives your immune response is the first step toward restoring balance.
Book your free 10-minute discovery call to discuss how we might work together, or dive in fully with an initial consultation.
For more information about fees and packages, visit our Fees & Bookings page